FGF21 ELISA Kit for Human(Homo sapiens) | EIAab.comFGF21 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FGF21(Gene name) > Human

FGF21 (Gene name),

Fibroblast growth factor 21 (Protein name ), FGF21_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FGF21(UNQ3115/PRO10196);

Protein name:

Fibroblast growth factor 21(FGF-21);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts (via C-terminus) with KLB; this interaction is direct. Interacts with FGFR4.

Function:

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

209

Sequence:

50:

100:

150:

200:

209:

QGRSPSYAS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9NSA1

KEGG:

hsa:26291

UniGene:

Hs.283015

Pfam:

PF00167

String:

Q9NSA1

MIM:

609436

STRING:

9606.ENSP00000222157

Uniprot:

Q9NSA1

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ELISA Kit for Human FGF-21

Cat.:

E0188h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human FGF-21

Cat.:

E0188m

Price:

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Human FGF-21

Cat.:

U0188m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human FGF-21

Cat.:

U0188h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human FGF-21

Cat.:

P0188Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human FGF-21

Cat.:

P0188Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human FGF-21

Protein for Human FGF-21

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Identification of a novel FGF, FGF-21, preferentially expressed in the liver."
Nishimura T. , Nakatake Y. , Konishi M. , Itoh N.
Biochim. Biophys. Acta1492:203-206(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

NIEHS SNPs program
Submitted (2006-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-141 AND PRO-174
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
6.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-43
7.

"FGF-21 as a novel metabolic regulator."
Kharitonenkov A. , Shiyanova T.L. , Koester A. , Ford A.M. , Micanovic R. , Galbreath E.J. , Sandusky G.E. , Hammond L.J. , Moyers J.S. , Owens R.A. , Gromada J. , Brozinick J.T. , Hawkins E.D. , Wroblewski V.J. , Li D.-S. , Mehrbod F. , Jaskunas S.R. , Shanafelt A.B.
J. Clin. Invest.115:1627-1635(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FGFR4 AND KLB
8.

"Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21."
Kurosu H. , Choi M. , Ogawa Y. , Dickson A.S. , Goetz R. , Eliseenkova A.V. , Mohammadi M. , Rosenblatt K.P. , Kliewer S.A. , Kuro-o M.
J. Biol. Chem.282:26687-26695(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors."
Wu X. , Lemon B. , Li X. , Gupte J. , Weiszmann J. , Stevens J. , Hawkins N. , Shen W. , Lindberg R. , Chen J.-L. , Tian H. , Li Y.
J. Biol. Chem.283:33304-33309(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KLB
10.

"Different roles of N- and C- termini in the functional activity of FGF21."
Micanovic R. , Raches D.W. , Dunbar J.D. , Driver D.A. , Bina H.A. , Dickinson C.D. , Kharitonenkov A.
J. Cell. Physiol.219:227-234(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KLB
11.

"Fibroblast growth factor signalling: from development to cancer."
Turner N. , Grose R.
Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW

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